6-aryl pyrido[2,3-d]pyrimidines and naphthyridines for...

Details 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines for... 6-aryl pyrido[2,3-d]pyrimidines and naphthyridines for...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2199964

6-Aryl pyrido[2,3-d]pyrimidines and naphthyridines are inhibitors of protein tyrosine kinase, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating atherosclerosis, restenosis, psoriasis, as well as bacterial infections.

Les 6-aryle pyrido[2,3-d]pyrimidines et les naphtyridines sont des inhibiteurs de la protéine tyrosine kinase, et conviennent ainsi au traitement de la prolifération cellulaire induite par cette dernière. Ces composés conviennent particulièrement au traitement de l'athérosclérose, de la resténose, du psoriasis, ainsi que des infections bactériennes.

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