6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors

Details 6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors 6-arylamino-5-cyano-4-pyrimidinones as pde9a inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 25/28 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2530461

The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I), methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.

L'invention concerne de nouvelles 6-arylamino-5-cyano-4-pyrimidinones de formule (I), des procédés pour leur production et leur utilisation pour la production de médicaments servant à améliorer la perception, la capacité de concentration, la capacité d'apprentissage et/ou de mémorisation. Les composés (I) agissent en tant qu'inhibiteurs de la PDE9A.

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