6-carboxy-flavone derivatives and process for their preparation

Details 6-carboxy-flavone derivatives and process for their preparation 6-carboxy-flavone derivatives and process for their preparation

C - Chemistry, Metallurgy

07

D

260/357.6, 260/3

C07D 311/30 (2006.01)

Patent

CA 1117957

Abstract of the Disclosure This invention relates to compounds which have the following formula (I) Image (I) wherein R, is a) carboxy or b) -COOR4, wherein R4 is C1-C12 alkyl or C3-C4 alkenyl; R2 is a') C1-C6 alkyl, which m?? be unsubstituted or substituted by C1-C2 alkoxy, or b') C3-C4 alkenyl; R3 ?? C1-C4 alkyl, and the pharmaceuti- cally acceptable salts with bases. It also relates to a process for the preparation of these compounds by the cyclization of a compound of formula (II) Image (II) and where this step may be followed by the conversion of a compound of general formula (I) into a pharmaceutically acceptable salt or, the conversion of a salt into a free compound of formula I. The compounds of this invention possess anti-allergic activity, which renders them useful in the prevention and treatment of bronchial asthma, allergic rhinitis, hay fever, urticaria and dermatosis.

289123

Affiliated with

Also associated with

Rating

6-carboxy-flavone derivatives and process for their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6-carboxy-flavone derivatives and process for their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-carboxy-flavone derivatives and process for their preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-769050