6'-epi derivatives of fortimicins a and b

Details 6'-epi derivatives of fortimicins a and b 6'-epi derivatives of fortimicins a and b

C - Chemistry, Metallurgy

07

H

260/300, 260/360

C07H 15/22 (2006.01) C07H 15/224 (2006.01)

Patent

CA 1128056

Abstract of the Disclosure 6'-Epi Fortimicin A and B derivatives represented by the formula Image wherein R1 is hydrogen or loweralkyl, R2 is hydrogen or loweralkyl and R3 is selected from the group consisting of hydrogen, loweralkyl, aminoloweralkyl, N-loweralkylamino- loweralkyl, N,N-diloweralkylaminoloweralkyl, aminohydroxy- loweralkyl, N-loweralkylaminohydroxyloweralkyl, hydroxylower- alkyl, acyl, aminoacyl, hydro?acyl, N-monoloweralkylamino- acyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an amino acid residue: the pharmaceutically acceptable salts thereof; intermediates useful in their preparation, compositions employing the compounds; and methods of using the compounds. The compounds are useful as antibiotics and antibacterial agents.

314115

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