C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/208, 167/243
C07D 405/14 (2006.01) A61K 31/335 (2006.01) A61K 31/395 (2006.01) C07D 303/22 (2006.01) C07D 405/12 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2011449
The present invention relates to a compound of the formula: (see formula I) wherein R1 is 2-methyl-1-propenyl group or isobutyl group; R2 is hydrogen atom, an optionally substituted aliphatic hydrocarbon residue or an optionally substituted acyl group or a salt thereof. The compound (I) of the invention has, among others, angiogenesis inhibiting activity, cell-proliferation inhibiting activity and immune reaction inhibiting activity, thus being useful as medicines, etc.
Fujita Takeshi
Kishimoto Shoji
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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