6-(-etherified oxyimino)acylamino penicillanic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 499/70 (2006.01) A61K 31/47 (2006.01) C07D 277/20 (2006.01) C07D 417/12 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1283097

Abstract The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: Image (I) wherein R1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.

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