6-fluoro-1,4-dihydro-4-oxo-7-(4-pyridyl)-1,8-...

Details 6-fluoro-1,4-dihydro-4-oxo-7-(4-pyridyl)-1,8-... 6-fluoro-1,4-dihydro-4-oxo-7-(4-pyridyl)-1,8-...

C - Chemistry, Metallurgy

07

D

167/231, 260/273

C07D 471/04 (2006.01) A61K 31/44 (2006.01)

Patent

CA 1250846

ABSTRACT OF THE INVENTION The invention provides for novel 7-(4-pyridyl)-1,8-naphthyridine derivatives of the formula (I) Image (I) wherein R1 is a hydrogen atom, an ethyl or vinyl group, and R2 is a hydrogen atom or a lower alkyl group having 1 to 6 carbon atoms, and processes for their preparation. The compounds of the invention exhibit superior anti- bacterial activity against Gram-positive bacteria such as Staphylococcus aureus, Gram-negative bacteria such as Escherichia coli and glucose-non- fermenters including Pseudomonas aeuroginosa.

433526

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