6 -heteroaryl-1, 2, 3,4,4a, 1ob-hexahydro-phenanthridines as...

Details 6 -heteroaryl-1, 2, 3,4,4a, 1ob-hexahydro-phenanthridines as... 6 -heteroaryl-1, 2, 3,4,4a, 1ob-hexahydro-phenanthridines as...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/473 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2598858

Compounds of a certain formula (I), in which R1 , R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.

La présente invention concerne des composés d~une certaine formule (I), où les significations de R1, R2, R3, R31, R4, R5, R51 et Har sont telles qu~indiquées dans la description, ces composés étant de nouveaux inhibiteurs efficaces de PDE4.

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