C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/36 (2006.01) A61K 31/12 (2006.01) A61K 31/352 (2006.01) A61K 31/353 (2006.01) A61P 1/00 (2006.01) A61P 7/00 (2006.01) A61P 9/00 (2006.01) A61P 13/08 (2006.01) A61P 15/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 37/00 (2006.01) C07C 39/373 (2006.01) C07C 45/46 (2006.01) C07C 49/245 (2006.01) C07C 49/248 (2006.01) C07C 49/83 (2006.01) C07C 49/835 (2006.01) C07D 311/38 (2006.01) C07D 311/58 (2006.01) C07D 311/64 (2006.01) C07D 311/74 (2006.01) C07D 471/06 (2006.01)
Patent
CA 2464593
Isoflavone compounds of the formula (I) or (II) Where R can be R7 or OR7 or O and the formula (III) is either a single or double bond extends to Y then Y is an optionally substituted benzyl. W, R1, Zo R2 and R7 are as defined in the specification. The compounds are useful for the treatment of certain diseases and disorders, including cancer and inflammation.
L'invention concerne des composés d'isoflavones des formules (I) ou (II) dans lesquelles R peut représenter R¿7? ou OR¿7? ou O et la formule (III) représente soit une simple liaison soit une double liaison. Y représente un cycle phényle facultativement substitué ou dans le cas où une double liaison s'étend jusqu'à Y alors Y représente benzyle facultativement substitué, W, R¿1?, Z¿0? R¿2?, R¿6? et R¿7? ont la notation définie dans la description. Les composés sont utiles au traitement de certaines maladies et de certains troubles notamment du cancer et de l'inflammation.
Heaton Andrew
Kelly Graham Edmund
Gowling Lafleur Henderson Llp
Novogen Research Pty Limited
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