6-modified bicyclic nucleic acid analogs

Details 6-modified bicyclic nucleic acid analogs 6-modified bicyclic nucleic acid analogs

C - Chemistry, Metallurgy

07

H

C07H 19/04 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2640171

The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either(R) or (S)-chirality at the 6- position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.

La présente invention concerne des analogues de nucléosides bicycliques modifiés en position 6 et des composés oligomères comprenant lesdits analogues. Sous des modes de réalisation préférés, les analogues de nucléosides présentent une chiralité de type (R) ou de type (S) en position 6. De tels analogues de nucléosides bicycliques ont démontré une utilité pour renforcer les propriétés de composés oligomères, notamment la résistance aux nucléases desdits composés oligomères.

Affiliated with

Also associated with

Rating

6-modified bicyclic nucleic acid analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 6-modified bicyclic nucleic acid analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-modified bicyclic nucleic acid analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1483452