6-monoacetylmorphine derivatives useful in immunoassay

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 489/00 (2006.01) C07D 489/02 (2006.01) G01N 33/531 (2006.01) G01N 33/58 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2571093

Analogs of 6-monoacetyl morphine (6-MAM) are described. These include analogs derivatized at either the C-3 position, the C-6 position, or the nor position of the molecule. These analogs allow for elaboration with linkers terminated by a functional group such as an activated ester, the functional groups being useful for attaching the molecule to other entities such as proteins, polysaccharides, and reporter groups.

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