C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/55 (2006.01) A61P 25/24 (2006.01) C07D 223/16 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2619450
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H- benzo[d]azepines of Formula I as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: Formula (I) where: R6 is selected from the group consisting of (a, b, c, d, e) and other substituents are as defined in the specification.
La présente invention propose des 2,3,4,5-tétrahydro-1H-benzo[d]azépines 6-substituées de formule I en tant qu'agonistes sélectifs de récepteur 5-HT2C pour le traitement de troubles associés à 5-HT2C comprenant l'obésité, les troubles obsessionnels compulsifs, la dépression, et l'anxiété : Formule (I) dans laquelle : R6 est choisi dans le groupe constitué de (a, b, c, d, e) et les autres substituants sont comme définis dans la spécification.
Briner Karin
Camp Anne Marie
Cornell Alan
Mazanetz Michael Philip
Rothhaar Roger Ryan
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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