6-o-alkyl erythromycin b oxime

Details 6-o-alkyl erythromycin b oxime 6-o-alkyl erythromycin b oxime

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2309963

A process of preparing a 6-O-alkyl derivative of 9-oxime erythromycin B is provided. Intermediates used in the preparation of a 6-O-alkyl 9-oxime erythromycin B are also provided. Pharmaceutical compositions containing a 6-O-alkyl derivative of 9-oxime erythromycin B and the use of those compositions to treat bacterial infections are also provided.

L'invention concerne un procédé de préparation d'un dérivé 6-O-alkyle de 9-oxime érythromycine B et les intermédiaires utilisés dans la préparation de 6-O-alkyle 9-oxime érythromycine B. L'invention concerne également des compositions pharmaceutiques contenant un dérivé 6-O-alkyle de 9-oxime érythromycine B et leur utilisation pour le traitement d'infections bactériennes.

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