C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01) A61K 31/7042 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2367431
The instant invention provides novel macrolide compounds and compositions useful in treating bacterial infections. Also provided are processes for preparing same. These macrolides are substituted on the 6-O- position with X'-Y'-Z', wherein X' is selected from the group consisting of C1-C10 alkyl, C3-C10 alkenyl, and C3-C10 alkynyl; Y' and Z' are independently selected from the group consisting of: (c) optionally substituted aryl, and (d) optionally substituted heteroaryl, with the proviso that both Y' and Z' are not both phenyl, and with the further proviso that Y' is not isoxazole when Z' is thiophenyl.
L'invention porte sur un nouveau composé de macrolides, sur des compositions servant à traiter les infections bactériennes, ainsi que sur leurs procédés de préparation. Lesdits macrolides sont substitués en position 6-O par X'-Y'-Z', où X' est choisi parmi C1-C10 alkyle, C3-C10 alcényle, et C3-C10 alkynyle; Y' et Z' sont choisis indépendamment parmi: (c) aryle facultativement substitué, et (d) hétéroaryle facultativement substitué, sous réserve que Y' et Z' ne soient pas tous deux phényle, et que Y' ne soit pas isoxazole quand Z' est thiophényle.
Clark Richard F.
Ma Zhenkun
Or Yat Sun
Rupp Michael J.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
6-o-substituted macrolides having antibacterial activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 6-o-substituted macrolides having antibacterial activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 6-o-substituted macrolides having antibacterial activity will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1526484