6-phenyl-3-(piperazinylalkyl)-2,4(1h,3h)- pyrimidinedione...

Details 6-phenyl-3-(piperazinylalkyl)-2,4(1h,3h)- pyrimidinedione... 6-phenyl-3-(piperazinylalkyl)-2,4(1h,3h)- pyrimidinedione...

C - Chemistry, Metallurgy

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C07D 401/14 (2006.01) A61K 31/505 (2006.01) C07D 239/54 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1327577

-33- ABSTRACT 6-PHENYL-3-(PIPERAZINYLALRYL)-2,4(1H,3H)-PYRIMIDINEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY A pyrimidinedione derivative which is a compound of formula (I): Image in which: R1 denotes hydrogen, a halogen, a methyl group or a methoxy group, R2 denotes hydrogen, a C1-C4 alkyl group or a benzyl group, n denotes 2, 3 or 4, X denotes a CH group or nitrogen, and R3 denotes hydrogen, a halogen or a methoxy group when X denotes a CH group, with the proviso that R3 denotes hydrogen when X denotes nitrogen, or a pharmacologically acceptable acid addition salt thereof.

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