6-phenylpyridyl-2-amine derivatives useful as nos inhibitors

Details 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors

C - Chemistry, Metallurgy

07

D

C07D 213/73 (2006.01) A61K 31/44 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2273479

The present invention relates to 6-phenyl-pyridin-2-ylamine derivatives of the formula (I) wherein G, R1 and R2 are defined as in the specification, that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central nervous system and other disorders.

La présente invention porte sur des dérivés de 6-phényl-pyridine-2-ylamine de la formule (I) dans laquelle G, R<1> et R<2> sont tels que définis dans la demande et agissent comme inhibiteurs de la synthase de l'oxyde nitrique (NOS). L'invention porte également sur des compositions pharmaceutiques les contenant et sur leur utilisation dans le traitement et la prévention des maladies du système nerveux central et autres pathologies.

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