6-phenylpyrrolopyrimidinedione derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) C07C 311/15 (2006.01) C07C 311/29 (2006.01) C07D 209/00 (2006.01) C07D 239/00 (2006.01) C07D 239/54 (2006.01) C07D 239/545 (2006.01) C07D 295/26 (2006.01)

Patent

CA 2411013

The invention relates to new 6-phenylpyrrolopyrimidine derivatives of formula (I): wherein -X-C-Y- represents (A) or -X-C-Y- represents (B) and to their use as selective cyclic GMP specific phosphodiesterase (PDE 5)inhibitors, processes for producing them, intermediates used in their production, compositions containing them and their applicability in medical treatment of the human or animal body.

L'invention concerne des dérivés 6-phényl-pyrrolo-pyrimidine représenté par la formule (I): dans laquelle -X-C-Y- représente (A) ou -X-C-Y- représente (B). L'invention concerne également l'utilisation desdits dérivés comme inhibiteurs de la phosphodiestérase (PDE 5) spécifique du GMP cyclique, des procédé de production desdits dérivés, des intermédiaires utilisés dans leur production, des compositions contenant lesdits dérivés et leur aptitude à être appliqués dans un traitement médical du corps humain ou d'un corps animal.

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