6-pyrrolidin-2-ylpyrindine derivatives, their preparation...

Details 6-pyrrolidin-2-ylpyrindine derivatives, their preparation... 6-pyrrolidin-2-ylpyrindine derivatives, their preparation...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2295666

The invention concerns a compound of general formula (I) in which: R1 represents a hydrogen atom, a (C1-C4) alkyl group or a phenyl (C1-C4) alkyl group optionally substituted; R2 represents a hydrogen atom or a (C1-C4) alkyl group; and R3, R4 and R5 represent each a hydrogen or halogen atom or a trifluoromethyl, cyano, hydroxy, (C1-C6) alkyl or (C1-C6) alkoxy group. The invention is applicable in therapy.

Composé répondant à la formule générale (I) dans laquelle: R¿1? représente un atome d'hydrogène, un groupe (C¿1?-C¿4?)alkyle ou un groupe phenyl (C¿1?-C¿4?)alkyle éventuellement substitué, R¿2? représente un atome d'hydrogène ou un groupe (C¿1?-C¿4?)alkyle, et R¿3?, R¿4? et R¿5? représentent chacun un atome d'hydrogène ou d'halogène ou un groupe trifluorométhyle, cyano, hydroxy, (C¿1?-C¿6?)alkyle ou (C¿1?-C¿6?)alcoxy. Application en thérapeutique.

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