6-substituted 1,2,4a,5a,8a,8b hexahydro- and...

Details 6-substituted 1,2,4a,5a,8a,8b hexahydro- and... 6-substituted 1,2,4a,5a,8a,8b hexahydro- and...

C - Chemistry, Metallurgy

07

D

C07D 491/14 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2289450

The invention relates to 6-substituted 1,2,4a,5a,8a,8b-hexahydro- and 1,2,3,4,4a,5a,8a,8b-octahydro-6h-pyrrolo[3',4':4,5]furo[3,2-b]pyrid-8 7H -on derivatives of general formula (I) and their salts, in which the radicals R1, R2, R3, R4, B and A have the meaning assigned to them in the description. The invention also relates to methods for their manufacture and their use in combatting endoparasites.

L'invention concerne des dérivés 1,2,4a,5a,8a,8b-hexahydro- et 1,2,3,4,4a,5a,8a,8b-octahydro-6H-pyrrolo[3',4';4,5]furo[3,2-b]pyride-8(7H)-one 6-substitués de la formule générale (I) et leurs sels. Dans cette formule, les restes R?1¿, R?2¿, R?3¿, R?4¿, B et A ont la signification mentionnée dans la description. L'invention concerne en outre des procédés permettant de les préparer et leur utilisation pour lutter contre des endoparasites.

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