6-substituted 2-(benzimidazolyl)purine and purinone...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/16 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61P 11/06 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01) C07D 473/18 (2006.01) C07D 473/32 (2006.01) C07D 473/40 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2735048

The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the genera formulae I and II wherein R1, R2, R3, R4, R9, Q, A and y are as defined in the specification.

La présente invention concerne de nouvelles purinones et purines utiles pour la prévention et le traitement de maladies auto-immunes, de maladie inflammatoire, de maladie médiée par les mastocytes et de rejet de transplant.

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