6-substituted 2-quinolinones and 2-quinoxalinones as...

C - Chemistry – Metallurgy – 07 – D

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C07D 241/44 (2006.01) A61K 31/498 (2006.01) A61P 43/00 (2006.01) C07D 401/12 (2006.01) C07D 407/06 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2546657

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, R1, R2, R3, R4, and X have defined meanings.

La présente invention concerne des composés représentés par la formule (I), leur utilisation comme inhibiteurs de la PARP ainsi que des compositions pharmaceutiques comprenant ces composés représentés par la formule (I) dans laquelle n, R?1¿, R?2¿, R?3¿, R?4¿ et X ont des significations définies.

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