6' substituted compounds having 5-ht6 receptor affinity

Details 6' substituted compounds having 5-ht6 receptor affinity 6' substituted compounds having 5-ht6 receptor affinity

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/496 (2006.01) A61K 31/4985 (2006.01) A61K 31/538 (2006.01) A61K 31/551 (2006.01) A61P 1/00 (2006.01) A61P 25/00 (2006.01) C07D 209/08 (2006.01) C07D 231/56 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2674087

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1-R4 A, B, D, E, and G are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

L'invention concerne des composés présentant une affinité avec le récepteur 5-HT6, de formule (I) dans laquelle : R1-R4 A, B, D, E et G sont tels que définis dans la description. L'invention concerne également des procédés de préparation de ces composés, des compositions les contenant, ainsi que des méthodes d'utilisation associées.

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