6-(substituted methylene) penems and intermediates

C - Chemistry – Metallurgy – 07 – D

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C07D 519/00 (2006.01) A61K 31/43 (2006.01) A61K 31/54 (2006.01) A61K 31/675 (2006.01) A61K 31/695 (2006.01) C07D 233/90 (2006.01) C07D 499/88 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01) C07F 7/22 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2147755

Compounds of formula (I) in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula (a) wherein R4 and R5 are independently hydrogen or one or more substituents replacing hydrogen atoms in the ring system shown; m is 2 or 3; p is 0, 1 or 2; and R3 is hydrogen, a salt-forming canon or an ester-forming group; and the symbol = / = indicates that the double bond may be in either the E or Z configuration.

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