6-substituted nicotinamide derivatives as opioid receptor...

Details 6-substituted nicotinamide derivatives as opioid receptor... 6-substituted nicotinamide derivatives as opioid receptor...

C - Chemistry, Metallurgy

07

D

C07D 213/82 (2006.01) A61K 31/4427 (2006.01) A61P 1/08 (2006.01) A61P 3/04 (2006.01) A61P 15/00 (2006.01) A61P 17/04 (2006.01) A61P 25/24 (2006.01) A61P 25/30 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2518194

A compound of the formula (I) or a pharmaceutically acceptable salt, enantiomer, racemate, diastereomers or mixtures thereof, or a solvate thereof, formulations and methods of use thereof, as opioid receptor antagonists are disclosed wherein the variables are as described herein.

L'invention concerne un composé représenté par la formule (I), ou un sel acceptable d'un point de vue pharmaceutique, un énantiomère, un racémate, des diastéréomères ou des mélanges de ceux-ci, ou un solvate de celui-ci, ainsi que des formulations et des procédés d'utilisation de celui-ci comme antagoniste des récepteurs des opioïdes, et ses variantes.

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