6-substituted thia-aza compounds

Details 6-substituted thia-aza compounds 6-substituted thia-aza compounds

C - Chemistry, Metallurgy

07

D

260/111, 167/188

C07D 499/00 (2006.01) A61K 31/43 (2006.01) C07D 205/08 (2006.01) C07D 205/09 (2006.01) C07D 499/88 (2006.01) C07F 9/568 (2006.01)

Patent

CA 1340273

The invention relates to 2-penem-3-carboxylic acid compounds of tile formula Image in which R a represents an organic radical bonded by a carbon atom to the ring carbon atom, a free, etherified or esterified hydroxy or mercapto group or a halogen atom, R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom, or an etherified mercapto group, and R2 represents a hydroxy group or an R A2 radical that together with the carbonyl grouping -C(=O)- forms a protected carboxyl group, and to salts of such compounds with salt-forming groups, processes for the manufacture of such compounds, pharmaceutical preparations containing compounds of the formula I with pharmacological properties, and their use. The compounds have antibiotic activity.

320618

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