6-sulfonyl chromans

Details 6-sulfonyl chromans 6-sulfonyl chromans

C - Chemistry, Metallurgy

07

D

260/357.5

C07D 311/70 (2006.01)

Patent

CA 1325216

ABSTRACT OF THE DISCLOSURE A class of novel chemical compounds comprising derivatives of 2,2,5,7,8-pentamethylchroman-6-sulphonyl and having the structural formula Image wherein X is selected from halogen and other groups having acidic functionality, and preferably the X-group being chlorine. The said compounds are made by the sulphonation of 2,2,5,7,8-pentamethylchroman, preferably using chlorosulphonic acid. The primary utility of the compounds of the present invention is in the protection of functional groups in organic synthesis and more particularly in the protection of basic functional amino groups, such as amidines and guanidines. The invention also provides a method of making the protecting group and a protected amino acid.

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