6-vinyl-furo-(3,4-c)-pyridine derivatives

Details 6-vinyl-furo-(3,4-c)-pyridine derivatives 6-vinyl-furo-(3,4-c)-pyridine derivatives

C - Chemistry, Metallurgy

07

D

260/276.2

C07D 491/048 (2006.01) A61K 31/435 (2006.01) C07D 491/04 (2006.01)

Patent

CA 1257271

A B S T R A C T This invention relates to new 1,3-dihydro-6-vinyl-7- hydroxy-furo-(3,4-c)-pyridine derivatives of the general formula : Image wherein each of A1 and A2 independently represents various hydrocarbon substituents, to a process for the preparation of these compounds from the corresponding 7-chloromethyl derivative and to pharmaceutical composition containing them, which are particularly active in the fields of selective diure- sis where their administration leads to a low K+ elimination associated with a high Na+ elimination and a uricosuric action.

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