C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/198 (2006.01) A61K 31/438 (2006.01) A61K 31/4725 (2006.01) A61K 31/495 (2006.01) A61P 25/30 (2006.01)
Patent
CA 2760837
Novel [l,2,4]triazolo[l,5-a]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SAl and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-I and N-2 are also described in the present invention.
La présente invention porte sur de nouvelles [l,2,4]triazolo[l,5-a]pyridinyl-6-yl-tétrahydroisoquinolines substituées. Ces composés et des formes cristallines SAl et N-2 sont utilisés dans le traitement de différents troubles neurologiques et physiologiques. L'invention porte également sur des procédés de fabrication de ces composés et des formes cristallines SA-I et N-2.
Liu Shuang
Molino Bruce F.
Nacro Kassoum
Albany Molecular Research Inc.
Gowling Lafleur Henderson Llp
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