C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/47 (2006.01)
Patent
CA 2179011
The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: Image wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; and (b) R' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo. The subject invention also involves the use of such compounds for preventing or treating other respiratory, ocular and/or gastrointestinal disorders. The subject invention also involves novel compounds having the above structure wherein R' is hydrogen or fluoro or cyano.
L'invention concerne des procédés de traitement de la congestion nasale par l'administration à un être humain ou à un animal inférieur ayant besoin d'un tel traitement d'une quantité sûre et efficace d'un composé ayant la sructure (I), dans laquelle (a) R désigne alcanyle ou alcényle C¿1?-C¿3? non substitués; et (b) R' est sélectionné parmi hydrogène, alcényle ou alcanyle C¿1?-C¿3? non substitués, alcoxy ou alcoylthio C¿1?-C¿3?, hydroxy, thiol, cyano et halo. L'invention concerne également l'utilisation de ces composés pour prévenir ou traiter d'autres troubles respiratoires, oculaires et/ou gastrointestinaux, ainsi que des composés nouveaux ayant la structure ci-dessus dans laquelle R' désigne hydrogène, fluoro ou cyano.
Bogdan Sophie Eva
Cupps Thomas Lee
Kirby Eades Gale Baker
The Procter & Gamble Company
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