7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-...

Details 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-... 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-...

C - Chemistry, Metallurgy

07

D

167/225, 260/273

C07D 401/04 (2006.01) A61K 31/435 (2006.01) C07D 471/04 (2006.01)

Patent

CA 1324141

ABSTRACT Novel, orally active antibacterial agents are described characterized as 7-[[3-(aminomethyl)-3-alkyl]- 1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acids or corresponding 1,8-naphthyridine derivatives as well as methods for their manufacture. The novel compounds have the general formula: Image wherein X is CH, CF, CCl, CNR3R4, or N; Y is H, OR4 or -NR3R4; R1 is hydrogen or alkyl from one to six carbon atoms; R2 is cyclopropyl or aryl; R3 is hydrogen, alkyl from one to three carbon atoms or cycloalkyl from three to six carbon atoms; R4 is hydrogen or alkyl from one to three carbon atoms; and R5 is alkyl from one to three carbon atoms or cycloalkyl from three to six carbon atoms; or a pharmaceutically acceptable acid addition or base salt thereof.

541356

Affiliated with

Also associated with

Rating

7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1179640