(7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine

Details (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine (7-(3-carboxyphenyl)-4-chloroisoquinolin-1-yl)guanidine

C - Chemistry, Metallurgy

07

D

C07D 217/22 (2006.01)

Patent

CA 2427613

The invention described herein relates to a process for the preparation of (7- (3-carboxypheniyl)-4-chloroisoquinolin-1-yl)guanidine (I), intermediates thereto and new forms and formulations thereof, including the zwitterion monohydrate of (I), suitable for pharmaceutical use. Formula (I).

La présente invention concerne un procédé de préparation de (7-(3-carboxyphényl)-4-chloroisoquinolin-1-yl)guanidine de formule (I), de produits intermédiaires associés et de nouvelles formes et formulations correspondantes, telles que le monohydrate zwitterionique du composé de formule (I). Les composés ainsi obtenus peuvent être destinés à un usage pharmaceutique.

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