7,9-substituted tetracycline compounds

Details 7,9-substituted tetracycline compounds 7,9-substituted tetracycline compounds

C - Chemistry, Metallurgy

07

C

C07C 237/26 (2006.01) A61K 31/65 (2006.01) C07D 209/48 (2006.01) C07D 213/82 (2006.01) C07D 215/14 (2006.01) C07D 307/24 (2006.01) C07D 317/60 (2006.01)

Patent

CA 2440383

The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

L'invention porte sur nouveaux composés de tétracycline substitués en position 7,9. Ces composés sont utilisés dans le traitement de nombreux états réagissant aux composés de tétracycline, telles que les infections bactériennes et les néoplasmes, ainsi que dans d'autres applications connues des composés de tétracycline et de minocycline en général, telles que le blocage de l'écoulement de tétracycline et la modulation de l'expression génétique.

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