7-alkylidene cephalosporanic acid derivatives and methods of...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/00 (2006.01) A61K 31/545 (2006.01)

Patent

CA 2206699

Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of .beta.-lactamase enzymes.

L'invention a pour objet des dérivés du sulfone d'acide 7-alkylidène céphalosporanique et les sels pharmaceutiquement actifs de ces derniers, qui constituent de puissants inhibiteurs des enzymes beta -lactamase.

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