7.alpha.-alkoxycarbonyl-15.beta., 16.beta.-methylene-4-...

Details 7.alpha.-alkoxycarbonyl-15.beta., 16.beta.-methylene-4-... 7.alpha.-alkoxycarbonyl-15.beta., 16.beta.-methylene-4-...

C - Chemistry, Metallurgy

07

J

260/21, 260/39

C07J 1/00 (2006.01) C07J 21/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1202615

ABSTRACT OF THE DISCLOSURE 7?-alkoxycarbonyl-15?,16?-methylene 4-androstene compounds of Formula I (I) Image wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, X is Image and Y is carbonyl, and the bond between the C-1 and C-2 carbon atoms is a single or double bond, or when the bond between the C-1 and C-2 carbon atoms is a single bond, X can also be Image when Y is Image possess valuable pharmacological properties, e.g., as aldosterone antagonists, i.e. they reverse the effect of deoxycorticosterone on the excretion of sodium and potassium.

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