7.alpha.-methoxycephalosporins and process for producing the...

Details 7.alpha.-methoxycephalosporins and process for producing the... 7.alpha.-methoxycephalosporins and process for producing the...

C - Chemistry, Metallurgy

07

D

260/102

C07D 501/57 (2006.01) C07D 241/08 (2006.01)

Patent

CA 1136615

ABSTRACT OF THE DISCLOSURE A 7.alpha.-methoxycephalosporin represented by the following general formula and a salt thereof: Image wherein R1 represents a hydrogen atom or a carboxyl- protecting group; R2 represents an organic group linked to the carbon atom through an oxygen or sulfur atom; R3 represents a lower alkyl group; n is 0, 1 or 2; A represents a substituted or unsubstituted alkyl group; R4 represents a lower alkyl group; and R5 represents a hydrogen atom or a hydroxyl-protecting group. These compounds have a broad antibacterial spectrum and high resistance to .beta.-lactamase produced from bacteria, and are well absorbed in a living body.

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