7-amine derivatives of 1-cyclopropyl-6,8-difluoro-1,4-...

Details 7-amine derivatives of 1-cyclopropyl-6,8-difluoro-1,4-... 7-amine derivatives of 1-cyclopropyl-6,8-difluoro-1,4-...

C - Chemistry, Metallurgy

07

D

167/208, 260/273

C07D 401/04 (2006.01) C07D 213/74 (2006.01) C07D 215/56 (2006.01) C07D 407/12 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 1285279

ABSTRACT Antibacterial agents such as 1-cyclopropyl-6,8- difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and 1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8- naphthyridine-3-carboxylic acids having amine sub- stituents on the 7-position are described as well as a method of manufacture, pharmaceutical composi- tions thereof and a method of treating bacterial infections therewith. Also described are novel intermediates used to prepare the various compounds with the amine substituents.

473501

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