7-amino-3-propenylcephalosporanic acid and esters thereof

Details 7-amino-3-propenylcephalosporanic acid and esters thereof 7-amino-3-propenylcephalosporanic acid and esters thereof

C - Chemistry, Metallurgy

07

D

260/101

C07D 501/18 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/02 (2006.01) C07D 501/04 (2006.01) C07D 501/16 (2006.01) C07D 501/22 (2006.01) C07D 513/04 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1273629

ABSTRACT This invention provides novel cephalosporin intermediates, 7.beta.-amino-3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid and esters thereof having the general formula Image wherein the configuration of the 3-propenyl group is Z sometimes referred to as cis- and R is hydrogen or a conventional carboxy-protecting group, and acid addition salts thereof and the metal salts of the foregoing substance wherein R is hydrogen. These compounds are useful as intermediates for preparation of orally active cephalosporins.

507037

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