7-amino-.delta.-3-cephem-4-carboxylic acid esters and...

C - Chemistry – Metallurgy – 07 – D

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C07D 501/18 (2006.01) A61K 31/545 (2006.01) C07D 501/04 (2006.01) C07D 501/60 (2006.01)

Patent

CA 1074299

ABSTRACT OF THE DISCLOSURE 7-amino- .DELTA. 3-cephem-4-carboxylic acid esters of the general formula I Image wherein R1 represents a five-membered heterocyclic ring containing one or two nitrogen atoms and one oxygen or sulfur atom, or is a five- membered heterocyclic ring containing three or four nitrogen atoms, or is a six-membered heterocyclic ring containing one to three nitrogen atoms and one sulfur atom , or is one of the afore- mentioned heterocyclic rings substituted by linear or branched C1-C8 alkyl, phenyl, C1-C4 alkoxyphenyl, nitrophenyl, or chloro- phenyl or wherein R1 is one of the aforementioned unsubstituted or substituted heterocyclic rings annellated to a benzene ring, and R2 stands for optionally substituted linear or branched alkyl, cycloalkyl, aryl, aralkyl, aryloxyalkyl, alkoxyalkyl, acyloxy- alkyl, aroylalkyl or a heterocyclic radical, and salts of these esters and a process for their manufacture.

212038

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