7-azaindole derivatives

Details 7-azaindole derivatives 7-azaindole derivatives

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2734398

The invention relates to novel 7-azaindole derivatives of formula (I) wherein U, L, R, Y, X1, X2 and X3 have the designations cited in claim (1). Said derivatives are kinase inhibitors and can be used to treat illnesses and complaints such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonal hypertonia, cardiovascular diseases and liver diseases, any type of fibrosis, inflammatory processes, tumours and tumour diseases.

L'invention concerne de nouveaux dérivés de 7-azaindole. Ces nouveaux dérivés de 7-azaindole de la formule (I), dans laquelle U, L, R, Y, X1,X2 et X3  ont les significations indiquées dans la revendication (1), sont des inhibiteurs de kinase et peuvent être utilisés pour le traitement de maladies et d'affections telles que diabète, obésité, syndrome métabolique (dyslipidémie), hypertonie systémique et pulmonaire, maladies cardiovasculaires et maladies rénales, en général pour tout type de fibroses, de processus inflammatoires, de tumeurs et de maladies tumorales.

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