7-keto or hydroxy 3,5-diene steroids as inhibitors of...

Details 7-keto or hydroxy 3,5-diene steroids as inhibitors of... 7-keto or hydroxy 3,5-diene steroids as inhibitors of...

C - Chemistry, Metallurgy

07

J

260/18, 167/191,

C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 3/00 (2006.01) C07J 7/00 (2006.01) C07J 9/00 (2006.01) C07J 13/00 (2006.01) C07J 31/00 (2006.01) C07J 43/00 (2006.01) C07J 73/00 (2006.01)

Patent

CA 2023609

ABSTRACT OF THE DISCLOSURE Invented are carboxyl and carboxyl alkyl ester substituted 7- keto and hydroxy analogues of synthetic steroidal compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5-.alpha.- reductase. Also invented are methods for preparing these compounds.

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