C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/08 (2006.01) A61K 31/551 (2006.01) A61P 5/28 (2006.01) A61P 9/00 (2006.01) A61P 9/02 (2006.01) A61P 9/10 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01) A61P 27/16 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 41/00 (2006.01) A61P 43/00 (2006.01) C07D 401/06 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2589638
A 7-membered heterocyclic compound represented by the formula (I): (I) a salt thereof, or a solvate of either. They have chymase inhibitory activity and are useful as a medicine for the prevention or treatment of various diseases in which chymase participates. Also provided is a medicinal composition which contains a compound of the formula (I), a pharmacologically acceptable salt thereof, or a solvate of either and is useful for the treatment or prevention of diseases in which chymase participates.
L'invention concerne un composé hétérocyclique à 7 chaînons représenté par la formule (I) : (I) un sel de celui-ci, ou un solvate de l'un ou l'autre. Ils possèdent une activité inhibitrice vis-à-vis de la chymase et sont utiles en tant que médicament pour la prévention ou le traitement de diverses affections dans lesquelles la chymase joue un rôle. L'invention a également trait à une composition médicinale qui contient un composé de la formule (I), un sel pharmacologiquement acceptable de celui-ci ou un solvate de l'un ou l'autre et qui est utile pour le traitement ou la prévention d'affections dans lesquelles la chymase joue un rôle.
Imajo Seiichi
Maruoka Hiroshi
Muto Tsuyoshi
Tanaka Taisaku
Tomimori Yoshiaki
Asubio Pharma Co. Ltd.
Daiichi Sankyo Company Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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