7-oxabicycloheptane substituted prostaglandin analogs

C - Chemistry – Metallurgy – 07 – D

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260/367, 260/361

C07D 493/18 (2006.01) C07D 493/08 (2006.01)

Patent

CA 1249288

ABSTRACT 7-OXABICYCLOHEPTANE SUBSTITUTED PROSTAGLANDIN ANALOGS 7-Oxabicycloheptane substituted prosta- glandin analogs are provided having the structural formula Image wherein A is O or S and R is CH2OH, Image or CO2H, and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

502618

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