7-oxabicycloheptane substituted thio prostaglandin analogs

Details 7-oxabicycloheptane substituted thio prostaglandin analogs 7-oxabicycloheptane substituted thio prostaglandin analogs

C - Chemistry, Metallurgy

07

D

167/205, 167/245

C07D 493/08 (2006.01) A61K 31/34 (2006.01) A61K 31/557 (2006.01)

Patent

CA 1257287

ABSTRACT 7-OXABICYCLOHEPTANE SUBSTITUTED THIO PROSTAGLANDIN ANALOGS 7-Oxabicycloheptane substituted thio prostaglandin analogs are provided having the structural formula Image wherein p is 0 to 4; A is CH=CH, (CH2)2, or a single bond; m is 0 to 8; R is H, lower alkyl, alkali metal or tris(hydroxymethyl)aminomethane; n is 1 to 4; n' is 0, 1 or 2; q is 1 to 12; X is Image , wherein R2 and R3 may be the same or different and are H or lower alkyl; t is 0 to 5; and R1 is H, lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, and including all stereoisomers thereof. The compounds are cardiovascular agents and antlinflammatory agents useful, for example, in the treatment of thrombolytlc diseasa, inflammation and pain.

482872

Affiliated with

Also associated with

Rating

7-oxabicycloheptane substituted thio prostaglandin analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-oxabicycloheptane substituted thio prostaglandin analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-oxabicycloheptane substituted thio prostaglandin analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1247203