7-oxadicycloheptane imino interphenyleneoxy substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/08 (2006.01) A61K 31/557 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2001159

HA478 Abstract 7-Oxabicycloheptane imino interphenyleneoxy substituted prostaglandin analogs are provided having the structural formula Image wherein n is 1 or 2; R is H, lower alkyl, or alkali metal; and R1 is -OR2, Image or Image where R2 is lower alkyl, aryl, aralkyl, alkanoyl or aroyl; and R3 is lower alkyl, aryl, aralkyl, alkoxy, aryloxy, aralkoxy, -NHaralkyl, -NHalkyl or -NHaryl.

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