7-oxo-4-thia-1-azabicyclo[3,2,0]heptane derivatives

Details 7-oxo-4-thia-1-azabicyclo[3,2,0]heptane derivatives 7-oxo-4-thia-1-azabicyclo[3,2,0]heptane derivatives

C - Chemistry, Metallurgy

07

D

260/327.3, 260/3

C07D 205/08 (2006.01) C07D 409/04 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1211118

Abstract of the Disclosure Compounds of the formula IIa, IIb and IIc Image wherein R represents a carboxyl esterifying group removable by hydrolysis, photolysis, reduction, or enzyme action to give the free acid R1 represents a chlorine or bromine atom, R2a and R2b, which may be the same or different, each represents an alkyl group having from 1 to 4 carbon atoms, an aryl group, and A represents a direct bond or the residue of a dicarboxylic acid and processes for their manufacture, are provided. These compounds are useful intermediates in the production of 7-oxo-4-thia-1-azabicyclo[3,2,0]-heptane and hept-2-ene derivatives, which in turn have antibacterial properties.

487761

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