7-phenylalkyl substituted 2-quinolinones and...

C - Chemistry – Metallurgy – 07 – D

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C07D 241/44 (2006.01) A61K 31/498 (2006.01) A61P 43/00 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2546002

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, R1, R2, R3, R4, R5, R6 and X have defined meanings.

La présente invention concerne des composés de formule (I), leur utilisation comme inhibiteurs PARP ainsi que des compositions pharmaceutiques renfermant lesdits composés de formule (I), dans laquelle n, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿ et X sont tels que définis dans le descriptif.

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