7-substituted-3,3a,4,5,6,7-hexahydro-3-substituted-2h-pyrazo...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) C07D 213/68 (2006.01)

Patent

CA 1049016

Abstract 7-substituted-3,3a,4,5,6,7-hexahydro-3-substituted- 2H-pyrazolo[4.3-a]pyridines of the formula Image wherein R and R3 are X-substituted phenyl, thienyl or pyridyl; R1 and R2 are hydrogen, lower alkyl, X1-substituted phenyl- lower alkyl, hydroxy lower alkyl or lower alkanoyl; X and X are hydrogen, chloro, fluoro, lower alkyl. lower alkoxy or trifluoromethyl: and N-oxides and acid addition salts thereof. The compounds and their N-oxides and acid addition salts thereof are useful as central nervous system depresants in mammals.

192668

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