"7-substituted 3-nitro-pyrazolo [1,5-a] pyrimidines"

Details "7-substituted 3-nitro-pyrazolo [1,5-a] pyrimidines" "7-substituted 3-nitro-pyrazolo [1,5-a] pyrimidines"

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 25/22 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2532431

The present invention relates to compounds of Formula (I): wherein R1 is as defined in the claims. The compounds have specific affinity for the GABAA receptor and are therefore useful in the treatment and prevention of diseases modulated by the .alpha.1- and .alpha.2- GABAA receptors.

Composés de formule (I) dans laquelle R¿1? est tel que défini dans les revendications. Lesdits composés possèdent une affinité spécifique pour le récepteur GABA<SB>A</SB> et sont par conséquent utiles pour traiter et prévenir des maladies modulées par les récepteurs GABA<SB>A</SB> .alpha.¿1? et .alpha.¿2?.

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