7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,...

Details 7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,... 7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,...

C - Chemistry, Metallurgy

07

D

167/180, 260/283

C07D 215/56 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2028869

7-(SUBSTITUTED)CYCLOALKYLAMINO-1- (SUBSTITUTED)-6-FLUORO-1.4-DIHYDRO-4- OXO-3-QUINOLINECARBOXYLIC ACIDS ABSTRACT Novel antibacterial compounds of the formula: Image in which R1 is alkyl (C1-C4), cycloalkyl (C3-C6), alkoxy (C1-C4), alkylamino (C1-C3), vinyl, phenyl, benzyl, -CH2CH2F or mono or polysubstituted phenyl (wherein the substituent is halogen, CF3 or OCH2F); n is an integer of from 1 to 4; and R2 is cis or trans hydroxy, amino, mono or disubstituted alkyl (C1-C3) amino and the pharmacologically accepted salts thereof are described.

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