7-substituted tetracycline compounds

Details 7-substituted tetracycline compounds 7-substituted tetracycline compounds

C - Chemistry, Metallurgy

07

C

C07C 237/26 (2006.01) A61K 31/65 (2006.01) C07C 251/24 (2006.01) C07C 251/48 (2006.01) C07C 271/22 (2006.01) C07C 271/28 (2006.01) C07C 271/58 (2006.01) C07C 275/24 (2006.01) C07C 311/06 (2006.01) C07D 207/22 (2006.01) C07D 213/50 (2006.01) C07D 213/56 (2006.01) C07D 213/64 (2006.01) C07D 239/36 (2006.01) C07D 261/18 (2006.01) C07D 277/30 (2006.01) C07D 277/42 (2006.01) C07D 295/096 (2006.01) C07D 295/135 (2006.01) C07D 295/155 (2006.01) C07D 307/54 (2006.01) C07D 307/68 (2006.01) C07D 307/79 (2006.01) C07D

Patent

CA 2415718

The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.

L'invention concerne, du moins en partie, des nouveaux composés de tétracycline substitués en 7. Ces composés peuvent être utilisés afin de traiter de nombreuses conditions réagissant au composé de tétracycline, telles que des infections bactériennes et des néoplasmes. L'invention concerne également d'autres applications connues des composés de minocycline et de tétracycline en général, telles que le blocage de l'efflux de tétracycline et la modulation de l'expression génique.

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